Updated By: LatestGKGS Desk
Indian researchers have isolated a strain of E.Coli bacteria, carrying a new gene (mcr -1), described previously as truly pan-drug resistant’ It is resistant to the last mile antibiotic the human race currently has access to - colistin.
The MCR-1 is a genetic mechanism by which the mcr-1 gene confers the first known plasmid-mediated resistance to colistin, a polymixin and one of a number of last-resort antibiotics.
This mechanism was first discovered in E. coli (strain SHP45) from a pig but it was later found by independent researchers in human samples. MCR-1 is the first known polymixin resistance mechanism capable of horizontal gene transfer.
The spread of the plasmid-mediated colistin resistance gene, mcr-1, into carbapenem-resistant Enterobacteriaceae (CRE) clinical isolates poses a significant threat to global health.
Mcr-1 gene is responsible for resistance against the antibiotic, Colistin which is considered as the last mile antibiotic that the human race has currently access to. Colistin belongs to a group of antibiotics called polymixins which are termed “critically important by WHO.
Mcr-1, the gene is found in the plasmid medium, a small DNA molecule outside of the chromosomal DNA and hence the infection can spread in hospitals and the community now.
Biology: Genetic disorder, sex-determining mechanism c...
Biology: The fingerprints of each individual differ fro...
Mutation: Definition, Genetic algorithm, testing, and theory...
Synthesis of the Protein from mRNA: Introduction, Steps, Ess...
Chromosomes: Introduction, Types of chromosomes, roles in th...
Histone Proteins: Introduction, Types, Works, Chemical &...
The transcription of the DNA molecule into mRNA, process, si...
DNA Replication, definition, procedure, steps, features, sig...
What is gel electrophoresis technique and what it is used fo...
Polymerase Chain Reaction Technique: Introduction, Mechanism...
Nobel Prize winner Francis Crick early life, education, DNA ...
Nobel Prize winner biophysicist J. D. Watson early life, res...
» Genetically Modified Crops (GMC) Disadvantages, Impact on Ecosystem and Health
» Genetically Modified Crops (GMC) Advantages, Benefits, Role in Crop Yields
» Genetically Modified Crops (GMC) History, Features, Role in Agriculture
» EU & India collaborates for research programme 'Horizon 2020' for Influenza Vaccine
» Scientists discover how brain function helps to fight bacteria
» Scientists extract medicine from spider silk to heal wounds
Privacy Policy | Twitter | RSS